Farmapram — Farmapram Side effects, Warning, Uses, Overdose
Farmapram is a benzodiazepine with a short half-life. This medication is being used to treat anxiety and panic attacks.
Benzodiazepines are a class of drugs that are primarily used to calm the brain by depressing the central nervous system. Farmapram is known by its generic name alprazolam in the United States and is popularly known by the brand name called Xanax.
Farmapram is a well-known brand in Mexico. It is a Schedule IV controlled substance that is physically addictive. Due to the fact that Farmapram has a high potential for abuse, addiction, and diversion, Farmapram is listed by the Drug Enforcement Agency (DEA) as a Schedule 4 Controlled Substance in the United States. Alprazolam and other benzodiazepine family members have high potential risks of abuse, overuse, addiction, physical dependency, and withdrawal symptoms.
Purchasing Farmapram on the internet or from a source outside the US can be risky and dangerous. The Food and Drug Administration’s safe-use guidelines may not be followed by pharmaceutical legislation from other countries (FDA). It’s possible that Farmapram medication bought from abroad is fake and may contain harmful substances, or come from an unlicensed pharmacy. Bringing these goods into the US from another country may be illegal.
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There are several limitations and other organizations that could have additional specifications or legal authority over a product. Before bringing in medicines that you purchased abroad, make sure to check with each organization.
What Is Farmapram Used For?
Farmapram is a benzodiazepine, which is used in the treatment of anxiety disorder. The US has the following FDA-approved uses for panic disorder and anxiety disorder.
Your doctor may also recommend alprazolam to treat “off-label” problems like:
insomnia depression nausea and vomiting brought on by chemotherapy
social phobia
Farmapram is also used to treat panic disorder, with or without agoraphobia.
Farmapram’s effectiveness has been indicated in systematic clinical studies for 4 months for generalized anxiety disorder and 4 to 10 weeks for panic disorder; however, patients with panic disorder have actually been treated on an open basis for 8 months without apparent benefit or loss. The physician should reassess the drug’s usefulness for the individual patient on a regular basis.
Alprazolam’s unapproved or “off-label” uses are those that have not been approved by the FDA and are not listed on the package labeling. However, some doctors may have had positive experiences using alprazolam “off-label,” and this might be an acceptable use even if it is not specifically listed on the product label.
Benzodiazepines can be dangerous and addictive, and should only be used if your doctor has specifically prescribed them for you.
When a benzodiazepine is combined with an opiate, it can cause profound sedation, slowed or stopped breathing coma, and death. Opiates include both prescription medications such as hydrocodone and illicit drugs such as heroin.
If you combine alprazolam with alcohol, opioid medication, or other drugs that cause drowsiness or slow your reaction time, you could die.
Side Effects
Side effects may occur at the start of therapy and then disappear once the treatment is stopped or the dose is adjusted.
These side effects vary depending on the disorder for which the drug is prescribed. The following are common side effects of Farmapram;
- Drowsiness, blurred Visual impairment impairs coordination
- Gastrointestinal problems (constipation, nausea)
- Reduced appetite
- Disorientation\confusion
- Dysarthria, headaches
- Depression
- Insomnia
- Sedation\fatigue
- Mood swings
- Body weight fluctuations
- Amnesia and memory loss
Drowsiness is the most common side effect of Farmapram (also known as alprazolam).
In children and the elderly, Farmapram can cause physical and mental dependence, rebound insomnia, anxiety-inducing anterograde amnesia, and psychiatric paradoxical reactions.
If you combine alprazolam with alcohol, opioids, or other medications that cause drowsiness and slow your breathing, you could have fatal side effects. Opioids include both prescription drugs like hydrocodone and oxycodone and illegal drugs like heroin.
The use of benzodiazepines and opioids can result in profound sedation, slow or irregular breathing, coma, and death.
It is not a treatment that is recommended for everyone. Patients with panic disorder, as well as those with severe depression and a proclivity to commit suicide, may benefit from high doses of Farmapram. Farmapram should never be given to children under the age of 18 and in ederly patients it is always advisable to use low doses.
Pregnant Women
There is insufficient data on Farmapram use in pregnant women. Farmapram should not be used during pregnancy unless the expected benefits to the mother outweigh the potential risks to the fetus. Children that were born when their mother used benzodiazepines during their last trimester may develop physical dependence or withdrawal syndrome.
There is no medical reason why the drug should be given in higher doses in the final stages of pregnancy, particularly after delivery, when effects on the newborn such as hypothermia, hypotension, and moderate respiratory disease may occur.
To rule out any negative effects, blood and urine tests may be required. It is critical that your doctor monitors your progress on a regular basis to ensure that the medication is effective.
Intercations
There are some drugs that could increase the side effects of Farmapram when they intereact together which includes;
- Central nervous system depressants drugs such as; oc80, t194, t189, Ip33
- Antihistamines such as; Texa pills, Alegra
- Cold medicines containing alcohol
- Sedatives
- Sleeping pills and prescription pain relievers
- Narcotics/barbiturates
- Anti-seizures
- Nausea, narcotics, and anaesthetic medications, including dental anaesthesia
These medications also slow down the heart rate, breathing, nervous system, and cause drowsiness. These side effects may last for a few days after stopping the medication.
Before taking any of the medications listed above, consult your doctor. If you experience unusual or strange thoughts or behaviors while taking this medication, consult your doctor.
Is Farmapram Harmful?
Farmapram is safe when prescribed and monitored by a doctor. It can make some people, especially the elderly, drowsy, dizzy, or less alert than usual. Other changes that may be unusual or extreme include:
confusion
depression
apparitions (seeing, hearing or feeling things that are not there)
Suicidal thoughts
unusual thrills
nervousness
irritability
Your doctor may advise you to reduce or discontinue the use of this medication. Gradually reducing your dosage can help prevent your condition from deteriorating and reduce the likelihood of withdrawal symptoms. Among the withdrawal symptoms are:
i. Behavioral modifications
ii. Discouragement
iii. Sadness or a sense of emptiness
iv. Irritability
v. Appetite loss of interest or pleasure
vi. Nausea
vii. Vomiting
viii. Hallucination
ix. Seizures/stremors
x. Cramps in the stomach
xi. Sweating
xii. Difficulties concentrating
xiii.Sleep disruptions
xiv. Movements, reactions, or expressions that are unusual or involuntary
Do not alter or discontinue your medication without first consulting your doctor. If you get dizzy, your vision is impaired, or you are not fully alert, make sure you consult your doctor immediately. how you are reacting to this medicine before driving a car or using a dangerous machine.
Symptoms of Farmapram Overdose
Overdose symptoms include unconsciousness, confusion, excessive drowsiness, and a loss of coordination. Call your doctor or emergency services right away for advice. If you believe the medication is not working, do not exceed the recommended dose.
If you notice any of these symptoms, contact your doctor right away. Taking this medication during pregnancy may cause withdrawal symptoms in your baby.
If your baby has abnormal sleep patterns, diarrhoea, violent screaming, irritability, tremor, weight loss, or vomiting, notify your doctor. Take no other medications until you have discussed them with your doctor.
Farmapram Dosage
To avoid overdosing or unpleasant side effects, only take Farmapram at the dose prescribed by your doctor.
THE DOSAGES BELOW SHOULD ONLY BE USED AS EXAMPLES; ALWAYS TAKE THE DOSE PRESCRIBED BY YOUR DOCTOR.
EXAMPLE: Adult Dose for Anxiety Disorder Immediate-release tablets/orally disintegrating tablets: 0.25 – 0.5mg orally 3 times per day
Maximum daily dose: 4mg
EXAMPLE: Adult Panic Disorder Dose Immediate-release tablets/orally disintegrating tablets: 0.5mg orally administered three times per day
The maximum daily dose is 10mg.
Tablets with extended release:
Initial dose: 0.5 – 1 mg orally once daily.
3 – 6 mg orally per day for maintenance
The maximum daily dose is 10mg.
Facts About Farmapram
Farmapram, is a drug for moderate to severe anxiety or for panic attacks.
It was given marketing approval in 1981. It’s considered a benzodiazepine sedative-hypnotic and a minor tranquilizer. Structurally, it’s similar to tricyclic antidepressant drugs like amitriptyline. The government classifies it as a Schedule IV drug. It was originally synthesized in 1957, but it just sat on the shelf because shortly after it was discovered, the same group of individuals discovered valium and put all the effort into Valium. It wasn’t until 20 years later that farmapram received a patent. It’s estimated more than 50 million prescriptions for the drug are currently used in the United States. It’s in the top 25 of all drugs. By 2010, it became the most frequently prescribed benzodiazepine and also the most abused. It was estimated that about 5% of the population takes some kind of medicine for anxiety.
The problem with this anxiety is that the definition changes over time. We have the American Psychiatric Association. They publish the Diagnostic and Statistical Manual, and every time they revised the book, they changed the definition of the disease.
And as a matter of fact, the American Psychiatric Association diagnosis differs from the International Classification of Disease diagnosis by the World Health Organization. How have we dealt with anxiety over time? Well, back in the 1910s it was heroin and opium morphine, then it was changed to phenobarbital, then in the 50s, it was Miltown, In the 60s, it was Valium. Actually, Valium was aggressively marketed as a consumer convenience. It was the first drug to reach more than $100 million in sales. But unfortunately, volume lingers in the system for more than 100 hours and gives you a hangover effect. You can feel like a zombie.
A lot of people are unable to feel and cry, or even taste when they take the drug. Then they found out about abuse, addiction, and dependence. So then in the 1980s, it was the SSRIs, and people became sort of disenchanted with them. Those are drugs like Prozac and Selects and Paxo. Then we changed to gabapentin and Lyrica and cannabis.
But through it all, since the early 1980s, it’s been Xanax. Xanax is an extraordinarily popular drug It’s used for anxiety, but it’s also used for panic. Panic is a condition that is devastating for a significant number of people. They have a variety of symptoms, they peak within several minutes causing a person not to be able to function. These people develop palpitations and pounding hearts. They have excessive sweating or sensation that they’re short of breath or that they’re smothering or that they’re choking they have chest pain, have a heart attack, going to die suffer from nausea, and abdominal distress, they feel dizzy, they become lightheaded and have chills or hot sensations. They also have numbness and tingling in different parts of the body, they fear they’re losing control, or going crazy, they fear that they’re dying. They tremble, shake, and oftentimes panic can be associated with major depressive disorder.
Farmapram is a chemical. We take it, it’s going to be absorbed very quickly. It’s going to be absorbed and reach maximum concentration in the bloodstream within about an hour or two. The half-life is about 11 hours ranging anywhere from 6 hours on the short side to 35 37 hours on the long side but tends to be about 1011 hours but it lasts a little bit longer in the elderly. That’s why we have to be more carefully prescribing this to people over age 65. If you have a liver disease it is going to stick around in your system for even longer and if you happen to be obese, even longer still. So the half-life and an obese individual ranges anywhere between 10 and 40 hours. The average is about 22 hours.
Now, the maximum concentration of farmapram in the system is going to be about 15% to 25% higher in Asians and the maximum concentration is going to be decreased by about 50% in people who are smoking cigarettes. It’s going to be metabolized in the liver and excreted in the urine. This medication is not appropriate for women who are pregnant. Women who are pregnant are a special case and unfortunately about half of the pregnancies in the United States are unplanned. So women don’t at least initially realize they are pregnant.
In the last trimester, if a woman has taken the drug it’s going to get into the fetus and the fetus can develop a dependency on the drug. And that means that after delivery the newborn can experience withdrawal symptoms neonatal, placidity, and respiratory problems. But if a woman discontinues the drug immediately, abruptly in pregnancy unfortunately there are extensive withdrawal syndromes that she might face. And then there’s the rebound of the underlying disorder. Special precautions are necessary in taking Xanax if a person is young if a person has a tendency to abuse either alcohol or drugs or if a person is old or if a person suffers from some comorbid disease stress, respiratory disease or psychiatric disease.
If you have obstructive sleep apnea or respiratory depression or cirrhosis or bipolar disorder or if you have a neurological condition known as myokymia gravis, this drug isn’t for you. And because it’s metabolized with enzymes in the liver, well, if those enzymes are changed, maybe because you’re taking Erythromycin or Clarithromycin or even pagant simitidine for your bad stomach, that’s going to change the way the Xanax is metabolized and might get you into trouble. A woman taking a breast control pill, it’s going to increase the concentration by about 20% of the Xanax in the system and prozac is going to increase the amount of Xanax in the system by about 50%.
The Xanax is going to increase the concentration of tricyclic antidepressants and unfortunately, a lot of people combine multiple different kinds of drugs. But you have to be careful, especially if you’re drinking alcohol. Remember, that can cause respiratory depression. This can cause respiratory we can have a problem. Kava, a popular herb, is not a drug that should be mixed with Xanax.
Now, tolerance occurs to the sedative or to the hypnotic effects of Xanax relatively quickly, oftentimes within several days. But it’s still going to be effective for treating anxiety and for treating panic. There is a GABA receptor that’s now sort of been nicknamed the benzodiazepine receptor.
It’s the most widespread inhibitory receptor inside the central nervous system and it mediates calming effects. Well, it has five subunits, and depending on how those five subunits are put together there are 19 choices for putting these five subunits together. Depending on how to put together that sort of determines how well the drug is going to work. There is a black box in the FDA warning and it warns that you should be extraordinarily cautious of taking Xanax with any of the opioids because that can result in profound respiratory distress or even coma and death. So you should use it only if all the other alternatives are inadequate.
You should limit the dose, you should limit the duration and you should watch for signs of respiratory depression. Well, what are the side effects of taking farmapram? Side effects are plenty. So depending on the individual some people develop disorientation or Malays or weakness or insomnia or racing heart or lightheadedness or dizziness or some people develop slurred speech or lack of coordination or fatigue or shallow breathing. They have impaired judgment or memory or coordination.
